Amphetamine is thought to inhibit monoamine oxidase, whereas the power of amphetamine and its metabolites to inhibit several P450 isozymes and various enzymes hasn't been adequately elucidated. In vitro experiments with human microsomes indicate minor inhibition of CYP2D6 by amphetamine and minimal inhibition of CYP1A2, 2D6, and 3A4 by one or more